Risk of neuroblastoma, maternal characteristics and perinatal exposures: The SETIL study
Highlights • Our case-control study contributes to the knowledge on the risk factors for neuroblastoma, a common paediatric malignancy. • The study was population based, including 1044 controls and 153 NB cases, being one of the largest on this disease. • Exposure during pregnancy to chemical produc...
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| Veröffentlicht in: | Cancer epidemiology 2014-12, Vol.38 (6), p.686-694 |
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| container_title | Cancer epidemiology |
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| creator | Parodi, Stefano Merlo, Domenico Franco Ranucci, Alessandra Miligi, Lucia Benvenuti, Alessandra Rondelli, Roberto Magnani, Corrado Haupt, Riccardo |
| description | Highlights • Our case-control study contributes to the knowledge on the risk factors for neuroblastoma, a common paediatric malignancy. • The study was population based, including 1044 controls and 153 NB cases, being one of the largest on this disease. • Exposure during pregnancy to chemical products or solvents increased the risk for neuroblastoma. • For mothers exposed to solvents OR was 2.0 (95%CI 1.0–4.1); for aromatic hydrocarbons OR was 9.2, 95%CI: 2.4–34.3. • OR for chemicals for domestic works or hair dye was higher for children 0–17 months (hair dye: OR = 5.5, 95%CI: 1.0–29.3). |
| doi_str_mv | 10.1016/j.canep.2014.09.007 |
| format | Article |
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Health state ; Biological and medical sciences ; Birth weight ; Cancer ; Case-Control Studies ; Children & youth ; Confidence intervals ; Congenital malformations ; ELF magnetic fields ; Epidemiology ; Female ; Gender ; General aspects ; Health risk assessment ; Hematology, Oncology and Palliative Medicine ; Humans ; Incidence ; Internal Medicine ; Interviews ; Kinases ; Lymphoma ; Magnetic fields ; Male ; Maternal characteristics ; Maternal Exposure - adverse effects ; Medical sciences ; Nervous System Malformations ; Neuroblastoma ; Neuroblastoma - diagnosis ; Neurofibromatosis ; Parental occupation ; Parents & parenting ; Polycyclic aromatic hydrocarbons ; Pregnancy ; Pregnancy Complications - etiology ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Questionnaires ; Risk Factors ; Solvents ; Tumors</subject><ispartof>Cancer epidemiology, 2014-12, Vol.38 (6), p.686-694</ispartof><rights>Elsevier Ltd</rights><rights>2014 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2014 Elsevier Ltd. All rights reserved.</rights><rights>Copyright Elsevier Limited 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c575t-ce7d54c973d71e885fb4f763dda8d3d06861b308caf4c1ea5ab1e45efa26a1453</citedby><cites>FETCH-LOGICAL-c575t-ce7d54c973d71e885fb4f763dda8d3d06861b308caf4c1ea5ab1e45efa26a1453</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S187778211400157X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28996312$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25280392$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Parodi, Stefano</creatorcontrib><creatorcontrib>Merlo, Domenico Franco</creatorcontrib><creatorcontrib>Ranucci, Alessandra</creatorcontrib><creatorcontrib>Miligi, Lucia</creatorcontrib><creatorcontrib>Benvenuti, Alessandra</creatorcontrib><creatorcontrib>Rondelli, Roberto</creatorcontrib><creatorcontrib>Magnani, Corrado</creatorcontrib><creatorcontrib>Haupt, Riccardo</creatorcontrib><creatorcontrib>SETIL Working Group</creatorcontrib><title>Risk of neuroblastoma, maternal characteristics and perinatal exposures: The SETIL study</title><title>Cancer epidemiology</title><addtitle>Cancer Epidemiol</addtitle><description>Highlights • Our case-control study contributes to the knowledge on the risk factors for neuroblastoma, a common paediatric malignancy. • The study was population based, including 1044 controls and 153 NB cases, being one of the largest on this disease. • Exposure during pregnancy to chemical products or solvents increased the risk for neuroblastoma. • For mothers exposed to solvents OR was 2.0 (95%CI 1.0–4.1); for aromatic hydrocarbons OR was 9.2, 95%CI: 2.4–34.3. • OR for chemicals for domestic works or hair dye was higher for children 0–17 months (hair dye: OR = 5.5, 95%CI: 1.0–29.3).</description><subject>Age</subject><subject>Analysis. Health state</subject><subject>Biological and medical sciences</subject><subject>Birth weight</subject><subject>Cancer</subject><subject>Case-Control Studies</subject><subject>Children & youth</subject><subject>Confidence intervals</subject><subject>Congenital malformations</subject><subject>ELF magnetic fields</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Gender</subject><subject>General aspects</subject><subject>Health risk assessment</subject><subject>Hematology, Oncology and Palliative Medicine</subject><subject>Humans</subject><subject>Incidence</subject><subject>Internal Medicine</subject><subject>Interviews</subject><subject>Kinases</subject><subject>Lymphoma</subject><subject>Magnetic fields</subject><subject>Male</subject><subject>Maternal characteristics</subject><subject>Maternal Exposure - adverse effects</subject><subject>Medical sciences</subject><subject>Nervous System Malformations</subject><subject>Neuroblastoma</subject><subject>Neuroblastoma - diagnosis</subject><subject>Neurofibromatosis</subject><subject>Parental occupation</subject><subject>Parents & parenting</subject><subject>Polycyclic aromatic hydrocarbons</subject><subject>Pregnancy</subject><subject>Pregnancy Complications - etiology</subject><subject>Public health. 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| fulltext | fulltext |
| identifier | ISSN: 1877-7821 |
| ispartof | Cancer epidemiology, 2014-12, Vol.38 (6), p.686-694 |
| issn | 1877-7821 1877-783X |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Age Analysis. Health state Biological and medical sciences Birth weight Cancer Case-Control Studies Children & youth Confidence intervals Congenital malformations ELF magnetic fields Epidemiology Female Gender General aspects Health risk assessment Hematology, Oncology and Palliative Medicine Humans Incidence Internal Medicine Interviews Kinases Lymphoma Magnetic fields Male Maternal characteristics Maternal Exposure - adverse effects Medical sciences Nervous System Malformations Neuroblastoma Neuroblastoma - diagnosis Neurofibromatosis Parental occupation Parents & parenting Polycyclic aromatic hydrocarbons Pregnancy Pregnancy Complications - etiology Public health. Hygiene Public health. Hygiene-occupational medicine Questionnaires Risk Factors Solvents Tumors |
| title | Risk of neuroblastoma, maternal characteristics and perinatal exposures: The SETIL study |
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