Risk of neuroblastoma, maternal characteristics and perinatal exposures: The SETIL study

Highlights • Our case-control study contributes to the knowledge on the risk factors for neuroblastoma, a common paediatric malignancy. • The study was population based, including 1044 controls and 153 NB cases, being one of the largest on this disease. • Exposure during pregnancy to chemical produc...

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Veröffentlicht in:Cancer epidemiology 2014-12, Vol.38 (6), p.686-694
Hauptverfasser: Parodi, Stefano, Merlo, Domenico Franco, Ranucci, Alessandra, Miligi, Lucia, Benvenuti, Alessandra, Rondelli, Roberto, Magnani, Corrado, Haupt, Riccardo
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Sprache:eng
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Zusammenfassung:Highlights • Our case-control study contributes to the knowledge on the risk factors for neuroblastoma, a common paediatric malignancy. • The study was population based, including 1044 controls and 153 NB cases, being one of the largest on this disease. • Exposure during pregnancy to chemical products or solvents increased the risk for neuroblastoma. • For mothers exposed to solvents OR was 2.0 (95%CI 1.0–4.1); for aromatic hydrocarbons OR was 9.2, 95%CI: 2.4–34.3. • OR for chemicals for domestic works or hair dye was higher for children 0–17 months (hair dye: OR = 5.5, 95%CI: 1.0–29.3).
ISSN:1877-7821
1877-783X
DOI:10.1016/j.canep.2014.09.007