Current status and prospects for development of a vaccine against Trichomonas vaginalis infections

Current status and prospects for development of a vaccine against Trichomonas vaginalis infections

Highlights • Most common non-viral and curable sexually transmitted infection globally. • A non-reportable, often asymptomatic infection that increases HIV transmission. • Underdiagnosis and under-recognition has lead to ongoing transmission and high incidence. • Drug resistance in Trichomonas vagin...

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Veröffentlicht in:Vaccine 2014-03, Vol.32 (14), p.1588-1594
Hauptverfasser: Smith, Jeffrey, Garber, Gary E
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Animals
Female
HIV Infections - transmission
HIV susceptibility
Human immunodeficiency virus
Humans
Immune response
Male
Trichomonas vaginalis
Trichomonas Vaginitis - prevention & control
Vaccination - trends
Vaccine development
Vaccines
Vaginitis
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Beschreibung
Zusammenfassung:Highlights • Most common non-viral and curable sexually transmitted infection globally. • A non-reportable, often asymptomatic infection that increases HIV transmission. • Underdiagnosis and under-recognition has lead to ongoing transmission and high incidence. • Drug resistance in Trichomonas vaginalis is a concern for the future. • An inexpensive vaccine for developing countries is needed and achievable.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2013.07.050