Response of incretins (GIP and GLP-1) to an oral glucose load in female and male subjects with normal glucose tolerance

Response of incretins (GIP and GLP-1) to an oral glucose load in female and male subjects with normal glucose tolerance

Abstract The aim of this study was to analyze the blood glucose profile and the response of incretins in healthy young subjects by the 75 g oral glucose tolerance test (OGTT). We first reported that plasma glucose and GIP levels were higher in males during the early phase of the OGTT.

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Veröffentlicht in:Diabetes research and clinical practice 2014-11, Vol.106 (2), p.e25-e29
Hauptverfasser: Matsuo, Toshihiro, Kusunoki, Yoshiki, Katsuno, Tomoyuki, Ikawa, Takashi, Akagami, Takafumi, Murai, Kazuki, Miuchi, Masayuki, Miyagawa, Jun-ichiro, Namba, Mitsuyoshi
Format: Artikel
Sprache:eng
Schlagworte:
75 g oral glucose tolerance test (OGTT)
Adult
Blood Glucose - analysis
Endocrinology & Metabolism
Enzyme-Linked Immunosorbent Assay
Female
Gastric Inhibitory Polypeptide - blood
Gastric Inhibitory Polypeptide - drug effects
Glucagon-like peptide 1 (GLP-1)
Glucagon-Like Peptide 1 - blood
Glucagon-Like Peptide 1 - drug effects
Glucose Tolerance Test
Glucose-dependent insulinotropic polypeptide (GIP)
Healthy Volunteers
Humans
Incretins - blood
Insulin - blood
Male
Young Adult
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Zusammenfassung:Abstract The aim of this study was to analyze the blood glucose profile and the response of incretins in healthy young subjects by the 75 g oral glucose tolerance test (OGTT). We first reported that plasma glucose and GIP levels were higher in males during the early phase of the OGTT.
ISSN:0168-8227
1872-8227
DOI:10.1016/j.diabres.2014.09.002