Development of Hyperthyroidism during Long Term Interferon Therapy in a Patient with Chronic Myelogenous leukemia: Case Report

In this case report a patient with thyroid dysfunction who received chronic treatment with interferon-alpha (INF-α) following a diagnosis of chronic myelogenous leukemia (CML) is described. Generally INF-α induced dysthyroidism develops in the earlier phase of INF-α treatment. This is a case report of thyroid dysfunction which occurred 4 years after the patient began to receive INF-α administration. In addition, INF-α was administered to this patient for a longer period than those reported in the literature.