The inhibitory effect of anthranilate derivatives on HCO sub(3) super(-)/Cl super(-) exchange in red blood cells of human, pigeon and trout

All ten of anthranilate derivatives were found to be inhibitors of HCO sub(3) super(-)/Cl super(-) exchange in human, trout and pigeon red blood cells. The individual I sub(50) values covered a range of 2-3 orders of magnitude for human, trout and pigeon RBCs. The results obtained confirm that the a...

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Veröffentlicht in:Cell biology international reports 1992-01, Vol.16 (6), p.575-584
Hauptverfasser: Romano, L, Mandolfino, M, Trischitta, F, Scuteri, A
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creator Romano, L
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Trischitta, F
Scuteri, A
description All ten of anthranilate derivatives were found to be inhibitors of HCO sub(3) super(-)/Cl super(-) exchange in human, trout and pigeon red blood cells. The individual I sub(50) values covered a range of 2-3 orders of magnitude for human, trout and pigeon RBCs. The results obtained confirm that the anion transporting region of the band 3 protein in human, trout and pigeon red blood cells are highly preserved even though the RBCs belong to animals living in entirely different habitats.
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ispartof Cell biology international reports, 1992-01, Vol.16 (6), p.575-584
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source Alma/SFX Local Collection
subjects anthranilic acid
bicarbonate
blood
carbon dioxide
chloride
effects on
erythrocytes
haematology
inhibitors
man
Oncorhynchus
transport
transport processes
title The inhibitory effect of anthranilate derivatives on HCO sub(3) super(-)/Cl super(-) exchange in red blood cells of human, pigeon and trout
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