The inhibitory effect of anthranilate derivatives on HCO sub(3) super(-)/Cl super(-) exchange in red blood cells of human, pigeon and trout

The inhibitory effect of anthranilate derivatives on HCO sub(3) super(-)/Cl super(-) exchange in red blood cells of human, pigeon and trout

All ten of anthranilate derivatives were found to be inhibitors of HCO sub(3) super(-)/Cl super(-) exchange in human, trout and pigeon red blood cells. The individual I sub(50) values covered a range of 2-3 orders of magnitude for human, trout and pigeon RBCs. The results obtained confirm that the a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell biology international reports 1992-01, Vol.16 (6), p.575-584
Hauptverfasser: Romano, L, Mandolfino, M, Trischitta, F, Scuteri, A
Format: Artikel
Sprache:eng
Schlagworte:
anthranilic acid
bicarbonate
blood
carbon dioxide
chloride
effects on
erythrocytes
haematology
inhibitors
man
Oncorhynchus
transport
transport processes
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:All ten of anthranilate derivatives were found to be inhibitors of HCO sub(3) super(-)/Cl super(-) exchange in human, trout and pigeon red blood cells. The individual I sub(50) values covered a range of 2-3 orders of magnitude for human, trout and pigeon RBCs. The results obtained confirm that the anion transporting region of the band 3 protein in human, trout and pigeon red blood cells are highly preserved even though the RBCs belong to animals living in entirely different habitats.
ISSN:0309-1651