Synthesis of kifunensine, an immunomodulating substance isolated from microbial source

A synthesis of kifunensine ( 1 ) has been achieved by a route involving, as a key step, a double cyclization of aldehyde 3 with ammonia. Kifunensine ( #1 ) has been synthesized via a double cyclization process (3→4) as the key step.

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Veröffentlicht in:Tetrahedron letters 1990, Vol.31 (2), p.225-226
Hauptverfasser: Kayakiri, Hiroshi, Kasahara, Chiyoshi, Oku, Teruo, Hashimoto, Masashi
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container_title Tetrahedron letters
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creator Kayakiri, Hiroshi
Kasahara, Chiyoshi
Oku, Teruo
Hashimoto, Masashi
description A synthesis of kifunensine ( 1 ) has been achieved by a route involving, as a key step, a double cyclization of aldehyde 3 with ammonia. Kifunensine ( #1 ) has been synthesized via a double cyclization process (3→4) as the key step.
doi_str_mv 10.1016/S0040-4039(00)94377-6
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subjects Chemistry
Exact sciences and technology
Heterocyclic compounds
Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings
Organic chemistry
Preparations and properties
title Synthesis of kifunensine, an immunomodulating substance isolated from microbial source
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