Synthesis of kifunensine, an immunomodulating substance isolated from microbial source

A synthesis of kifunensine ( 1 ) has been achieved by a route involving, as a key step, a double cyclization of aldehyde 3 with ammonia. Kifunensine ( #1 ) has been synthesized via a double cyclization process (3→4) as the key step.

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Veröffentlicht in:Tetrahedron letters 1990, Vol.31 (2), p.225-226
Hauptverfasser: Kayakiri, Hiroshi, Kasahara, Chiyoshi, Oku, Teruo, Hashimoto, Masashi
Format: Artikel
Sprache:eng
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Zusammenfassung:A synthesis of kifunensine ( 1 ) has been achieved by a route involving, as a key step, a double cyclization of aldehyde 3 with ammonia. Kifunensine ( #1 ) has been synthesized via a double cyclization process (3→4) as the key step.
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(00)94377-6