Five-year real world outcomes of GeoForm ring implantation in patients with ischemic mitral regurgitation
Background Reductive ring annuloplasty represents the current standard surgical therapy for ischemic mitral regurgitation (IMR); however, the clinical results have been suboptimal. Etiology-specific prostheses such as the GeoForm annuloplasty ring have been designed to better address the annular and...
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Veröffentlicht in: | The Journal of thoracic and cardiovascular surgery 2014-11, Vol.148 (5), p.1951-1956 |
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Sprache: | eng |
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Zusammenfassung: | Background Reductive ring annuloplasty represents the current standard surgical therapy for ischemic mitral regurgitation (IMR); however, the clinical results have been suboptimal. Etiology-specific prostheses such as the GeoForm annuloplasty ring have been designed to better address the annular and subvalvular perturbations associated with IMR. However, clinical experience is limited, and mid-term results are lacking. Methods We reviewed the clinical outcomes of 86 patients who had undergone implantation of a GeoForm ring at our center from 2005 to 2011. Perioperative mortality and clinical parameters were derived from The Society of Thoracic Surgeons database. Follow-up survival was assessed using the Social Security Death Index. Surviving patients were interviewed by telephone for valve-specific follow-up data and to complete the Medical Outcomes Study, short-form, 36-item, quality-of-life questionnaire. Results The mean grade of IMR preoperatively was 3.1 ± 0.8 (range, 1-4+), 0.2 ± 0.4 in the immediate postoperative period, and 0.7 ± 0.7 at the last mean follow-up point of 41 months; only 2 patients developed ≥2+ IMR during the follow-up period, for a 5-year freedom from recurrent 2+ IMR of 86%. The mean left ventricular end-diastolic and end-systolic diameters decreased from before to after surgery from 6.0 ± 0.0 cm to 5.3 ± 09 cm and 5.0 ± 0.9 cm to 4.3 ± 1.1 cm, respectively ( P |
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ISSN: | 0022-5223 1097-685X |
DOI: | 10.1016/j.jtcvs.2014.02.051 |