Five-year real world outcomes of GeoForm ring implantation in patients with ischemic mitral regurgitation

Background Reductive ring annuloplasty represents the current standard surgical therapy for ischemic mitral regurgitation (IMR); however, the clinical results have been suboptimal. Etiology-specific prostheses such as the GeoForm annuloplasty ring have been designed to better address the annular and...

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Veröffentlicht in:The Journal of thoracic and cardiovascular surgery 2014-11, Vol.148 (5), p.1951-1956
Hauptverfasser: Timek, Tomasz A., MD, Hooker, Robert L., MD, Collingwood, Robin, MD, Davis, Alan T., PhD, Alguire, Craig T., MD, Willekes, Charles L., MD, Murphy, Edward T., MD, Heiser, John C., MD, Patzelt, Lawrence H., MD
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Sprache:eng
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Zusammenfassung:Background Reductive ring annuloplasty represents the current standard surgical therapy for ischemic mitral regurgitation (IMR); however, the clinical results have been suboptimal. Etiology-specific prostheses such as the GeoForm annuloplasty ring have been designed to better address the annular and subvalvular perturbations associated with IMR. However, clinical experience is limited, and mid-term results are lacking. Methods We reviewed the clinical outcomes of 86 patients who had undergone implantation of a GeoForm ring at our center from 2005 to 2011. Perioperative mortality and clinical parameters were derived from The Society of Thoracic Surgeons database. Follow-up survival was assessed using the Social Security Death Index. Surviving patients were interviewed by telephone for valve-specific follow-up data and to complete the Medical Outcomes Study, short-form, 36-item, quality-of-life questionnaire. Results The mean grade of IMR preoperatively was 3.1 ± 0.8 (range, 1-4+), 0.2 ± 0.4 in the immediate postoperative period, and 0.7 ± 0.7 at the last mean follow-up point of 41 months; only 2 patients developed ≥2+ IMR during the follow-up period, for a 5-year freedom from recurrent 2+ IMR of 86%. The mean left ventricular end-diastolic and end-systolic diameters decreased from before to after surgery from 6.0 ± 0.0 cm to 5.3 ± 09 cm and 5.0 ± 0.9 cm to 4.3 ± 1.1 cm, respectively ( P  
ISSN:0022-5223
1097-685X
DOI:10.1016/j.jtcvs.2014.02.051