Influenza vaccine effectiveness estimates for Western Australia during a period of vaccine and virus strain stability, 2010 to 2012

Highlights • Data were pooled across 2010–2012, years during which the vaccine composition was unaltered. • Vaccine effectiveness estimates were made by year and subtype and indicated no significant decline in vaccine effectiveness across years. • Estimates were highest against H1 and lowest against...

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Veröffentlicht in:Vaccine 2014-10, Vol.32 (47), p.6312-6318
Hauptverfasser: Levy, Avram, Sullivan, Sheena G, Tempone, Simone S, Wong, Kerry L.M, Regan, Annette K, Dowse, Gary K, Effler, Paul V, Smith, David W
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container_end_page 6318
container_issue 47
container_start_page 6312
container_title Vaccine
container_volume 32
creator Levy, Avram
Sullivan, Sheena G
Tempone, Simone S
Wong, Kerry L.M
Regan, Annette K
Dowse, Gary K
Effler, Paul V
Smith, David W
description Highlights • Data were pooled across 2010–2012, years during which the vaccine composition was unaltered. • Vaccine effectiveness estimates were made by year and subtype and indicated no significant decline in vaccine effectiveness across years. • Estimates were highest against H1 and lowest against H3. • When using noninfluenza virus-positive controls VE estimates were slightly higher, perhaps owing to improvements in outcome sensitivity. • Comparison of estimates within and out of the season suggested little effect of the vaccine outside the season.
doi_str_mv 10.1016/j.vaccine.2014.08.066
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subjects Adolescent
Adult
Aged
Aged, 80 and over
Allergy and Immunology
Applied microbiology
Biological and medical sciences
Case-Control Studies
Child
Child, Preschool
Data pooling
Estimates
Family medical history
Female
Fundamental and applied biological sciences. Psychology
Humans
Illnesses
Infant
Infant, Newborn
Influenza
Influenza A Virus, H1N1 Subtype
Influenza A Virus, H3N2 Subtype
Influenza B virus
Influenza season
Influenza vaccine
Influenza Vaccines - immunology
Influenza Vaccines - therapeutic use
Influenza virus
Influenza, Human - epidemiology
Influenza, Human - prevention & control
Influenza, Human - virology
Influenza-like illness
Laboratories
Male
Microbiology
Middle Aged
Odds Ratio
Patients
Sentinel Surveillance
Surveillance
Vaccine effectiveness
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
Viruses
Western Australia - epidemiology
Young Adult
title Influenza vaccine effectiveness estimates for Western Australia during a period of vaccine and virus strain stability, 2010 to 2012
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