Contribution of Recurrent Venous Thrombosis and Inherited Thrombophilia to the Pathogenesis of Postthrombotic Syndrome

Contribution of Recurrent Venous Thrombosis and Inherited Thrombophilia to the Pathogenesis of Postthrombotic Syndrome

Postthrombotic syndrome (PTS) is a common complication of deep vein thrombosis. This study aims to assess the role of recurrent venous thrombosis and inherited thrombophilia in the pathogenesis of PTS. A series of 206 patients diagnosed with lower extremity venous thrombosis were retrospectively rev...

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Veröffentlicht in:Clinical and applied thrombosis/hemostasis 2015-01, Vol.21 (1), p.87-90
1. Verfasser: Kreidy, Raghid
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Aged, 80 and over
Female
Health risk assessment
Humans
Male
Middle Aged
Pathogenesis
Postthrombotic Syndrome - etiology
Postthrombotic Syndrome - physiopathology
Recurrence
Retrospective Studies
Risk Factors
Thrombophilia - complications
Thrombosis
Vascular Surgical Procedures
Venous Thrombosis - complications
Venous Thrombosis - surgery
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Beschreibung
Zusammenfassung:Postthrombotic syndrome (PTS) is a common complication of deep vein thrombosis. This study aims to assess the role of recurrent venous thrombosis and inherited thrombophilia in the pathogenesis of PTS. A series of 206 patients diagnosed with lower extremity venous thrombosis were retrospectively reviewed. The PTS was observed in 30.58% of the patients. Recurrent venous thrombosis was identified in 3.4% of the patients without PTS and in 33.3% of patients with PTS (P < .001). Inherited thrombophilia alone or in association with recurrent venous thrombosis was more commonly detected when PTS was moderate to severe (P = .04 and
ISSN:1076-0296
1938-2723
DOI:10.1177/1076029613497423