First evaluation of a multi-capillary electrophoresis CDT assay on Helena Biosciences' V8 analyser

Carbohydrate-deficient transferrin measurement is currently used for the routine monitoring of excessive alcohol intake, thus playing a fundamental role in the management of alcohol consumption disorders as well as for medico-legal purposes. The aim of the present paper is to report the results obtained from the first performance evaluation of a new CDT quantification assay, and to assess its suitability in routine work. We assessed the analytical performances of the multi-capillary electrophoresis analyser Helena Biosciences' V8® E-class and compared the results obtained with those from the HPLC BioRad Ready-Prep CDT assay. Furthermore, we evaluated the robustness of the system in a routine work conditions. Within laboratory imprecision CV% (n=40) using four commercially available quality control materials and two serum pool samples with different concentrations of CDT were