Impaired mastication reduced newly generated neurons at the accessory olfactory bulb and pheromonal responses in mice

Impaired mastication reduced newly generated neurons at the accessory olfactory bulb and pheromonal responses in mice

Highlights • Mastication is impaired by offering animals only a soft diet. • BrdU- and Fos-immunoreactive structures in the AOB of female mice fed a soft were studied to explore the effects of changes in mastication. • Impaired mastication decreased newly generated neurons at the accessory olfactory...

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Veröffentlicht in:Archives of oral biology 2014-12, Vol.59 (12), p.1272-1278
Hauptverfasser: Utsugi, Chizuru, Miyazono, Sadaharu, Osada, Kazumi, Matsuda, Mitsuyoshi, Kashiwayanagi, Makoto
Format: Artikel
Sprache:eng
Schlagworte:
Advanced Basic Science
Animals
Bromodeoxyuridine
Dentistry
Diet
Female
Hard diet
Immunohistochemistry
Male
Mastication
Mastication - physiology
Mice
Mice, Inbred C57BL
Neurogenesis - physiology
Olfactory Bulb - cytology
Olfactory Bulb - physiology
Olfactory function
Pheromone
Pheromones - urine
Proto-Oncogene Proteins c-fos
Smell - physiology
Soft diet
Time Factors
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Zusammenfassung:Highlights • Mastication is impaired by offering animals only a soft diet. • BrdU- and Fos-immunoreactive structures in the AOB of female mice fed a soft were studied to explore the effects of changes in mastication. • Impaired mastication decreased newly generated neurons at the accessory olfactory bulb. • Impaired mastication reduced pheromonal responses at the accessory olfactory bulb.
ISSN:0003-9969
1879-1506
DOI:10.1016/j.archoralbio.2014.07.018