DuraSeal® as a spacer to reduce rectal doses in low-dose rate brachytherapy for prostate cancer

Abstract The purpose of this study was to evaluate the utility of off-label use of DuraSeal® polyethylene glycol (PEG) gel in low-dose rate (LDR) prostate brachytherapy seed implantation to reduce rectal doses. Diluted DuraSeal® was easy to use and, in spite of a clearance effect, useful in decreasi...

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Veröffentlicht in:	Radiotherapy and oncology 2014-08, Vol.112 (2), p.233-236
Hauptverfasser:	Heikkilä, Vesa-Pekka, Kärnä, Aarno, Vaarala, Markku H
Format:	Artikel
Sprache:	eng
Schlagworte:	Brachytherapy Brachytherapy - methods Clinical trial Dose-Response Relationship, Radiation Hematology, Oncology and Palliative Medicine Humans Iodine Radioisotopes - therapeutic use Male Polyethylene glycol gel Prostatic Neoplasms - radiotherapy Radiation side effect Radiation-Protective Agents - administration & dosage Radiation-Protective Agents - adverse effects Rectum - drug effects Rectum - radiation effects Resins, Synthetic - administration & dosage Resins, Synthetic - adverse effects
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Beschreibung
Zusammenfassung:	Abstract The purpose of this study was to evaluate the utility of off-label use of DuraSeal® polyethylene glycol (PEG) gel in low-dose rate (LDR) prostate brachytherapy seed implantation to reduce rectal doses. Diluted DuraSeal® was easy to use and, in spite of a clearance effect, useful in decreasing D2cc rectal doses.
ISSN:	0167-8140 1879-0887
DOI:	10.1016/j.radonc.2014.08.012