Myxofibrosarcoma of the thyroid gland

Abstract Introduction Myxofibrosarcoma of the thyroid is exceptional: a Medline search found a single case report. We report a new case which raised diagnostic and therapeutic problems. Observation We report the case of a 74-year-old woman who presented with swelling of the left thyroid lobe and ips...

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Veröffentlicht in:European annals of otorhinolaryngology, head and neck diseases head and neck diseases, 2014-12, Vol.131 (6), p.385-387
Hauptverfasser: Darouassi, Y, Attifi, H, Zalagh, M, Rharrassi, I, Benariba, F
Format: Artikel
Sprache:eng
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Zusammenfassung:Abstract Introduction Myxofibrosarcoma of the thyroid is exceptional: a Medline search found a single case report. We report a new case which raised diagnostic and therapeutic problems. Observation We report the case of a 74-year-old woman who presented with swelling of the left thyroid lobe and ipsilateral cervical lymphadenopathy. Total thyroidectomy with cervical lymph-node dissection was performed. Histological analysis diagnosed myxofibrosarcoma. Evolution was marked by rapid local recurrence, and chemotherapy based on doxorubicin and ifosfamide was introduced. Discussion/conclusion Head and neck myxofibrosarcoma is rare. MRI is essential and should always precede treatment. Diagnosis is histological. There is elevated risk of local recurrence after resection, accompanied by worsening tumor grade, whence the need for accurate diagnosis, appropriate treatment and regular MRI follow-up.
ISSN:1879-7296
1879-730X
DOI:10.1016/j.anorl.2013.09.004