Prevention of binding of rgp120 by anti-HIV active tannins

Several tannins with anti-HIV activity have been described previously (Nonaka et al., J Nat Prod 53: 587–595, 1990). We have shown that the tannins chebulinic acid and punicalin were able to block the binding of HIV rgpl20 to CD4. These compounds were not toxic to stimulated human peripheral blood l...

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