Acetylsalicylic acid enhances the anti-inflammatory effect of fluoxetine through inhibition of NF-κB, p38-MAPK and ERK1/2 activation in lipopolysaccharide-induced BV-2 microglia cells
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Veröffentlicht in: | Neuroscience 2014-09, Vol.275, p.296-304 |
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container_title | Neuroscience |
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creator | Yang, J.M Rui, B.B Chen, C Chen, H Xu, T.J Xu, W.P Wei, W |
description | Graphical abstract |
doi_str_mv | 10.1016/j.neuroscience.2014.06.016 |
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subjects | Animals Anti-Inflammatory Agents - pharmacology Antidepressive Agents, Second-Generation - pharmacology Aspirin - pharmacology Blotting, Western Cell Line Cell Survival - drug effects Enzyme-Linked Immunosorbent Assay Fluoxetine - pharmacology Immunohistochemistry Inflammation - chemically induced Inflammation - metabolism Lipopolysaccharides - toxicity MAP Kinase Signaling System - drug effects Mice Microglia - drug effects Microglia - metabolism Neurology NF-kappa B - drug effects NF-kappa B - metabolism p38 Mitogen-Activated Protein Kinases - drug effects p38 Mitogen-Activated Protein Kinases - metabolism Signal Transduction - drug effects |
title | Acetylsalicylic acid enhances the anti-inflammatory effect of fluoxetine through inhibition of NF-κB, p38-MAPK and ERK1/2 activation in lipopolysaccharide-induced BV-2 microglia cells |
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