Acetylsalicylic acid enhances the anti-inflammatory effect of fluoxetine through inhibition of NF-κB, p38-MAPK and ERK1/2 activation in lipopolysaccharide-induced BV-2 microglia cells

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Veröffentlicht in:	Neuroscience 2014-09, Vol.275, p.296-304
Hauptverfasser:	Yang, J.M, Rui, B.B, Chen, C, Chen, H, Xu, T.J, Xu, W.P, Wei, W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Antidepressive Agents, Second-Generation - pharmacology Aspirin - pharmacology Blotting, Western Cell Line Cell Survival - drug effects Enzyme-Linked Immunosorbent Assay Fluoxetine - pharmacology Immunohistochemistry Inflammation - chemically induced Inflammation - metabolism Lipopolysaccharides - toxicity MAP Kinase Signaling System - drug effects Mice Microglia - drug effects Microglia - metabolism Neurology NF-kappa B - drug effects NF-kappa B - metabolism p38 Mitogen-Activated Protein Kinases - drug effects p38 Mitogen-Activated Protein Kinases - metabolism Signal Transduction - drug effects
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