Corticofugal projections from medial primary somatosensory cortex avoid EphA7-expressing neurons in striatum and thalamus

Highlights • Corticostriatal projections from the medial somatosensory cortex avoid EphA7-expressing neurons in the striatum. • Corticothalamic projections from the somatosensory cortex also avoid EphA7-expressing neurons in the thalamus. • EphA7–ephrinA interactions mediate corticofugal terminal to...

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Veröffentlicht in:	Neuroscience 2014-08, Vol.274, p.409-418
Hauptverfasser:	Tai, A.X, Kromer, L.F
Format:	Artikel
Sprache:	eng
Schlagworte:	anatomy Animals Biological and medical sciences Biotin - analogs & derivatives Corpus Striatum - anatomy & histology Corpus Striatum - metabolism corticostriatal corticothalamic Dextrans Electron Transport Complex IV - metabolism ephrin Fundamental and applied biological sciences. Psychology Immunohistochemistry matrisome matrix Mice, 129 Strain Mice, Inbred C57BL Neural Pathways - anatomy & histology Neural Pathways - metabolism Neuroanatomical Tract-Tracing Techniques Neurology Neurons - cytology Neurons - metabolism Receptor, EphA7 - metabolism Somatosensory Cortex - anatomy & histology Somesthesis and somesthetic pathways (proprioception, exteroception, nociception) interoception electrolocation. Sensory receptors Thalamus - anatomy & histology Thalamus - metabolism Vertebrates: nervous system and sense organs Vibrissae
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Zusammenfassung:	Highlights • Corticostriatal projections from the medial somatosensory cortex avoid EphA7-expressing neurons in the striatum. • Corticothalamic projections from the somatosensory cortex also avoid EphA7-expressing neurons in the thalamus. • EphA7–ephrinA interactions mediate corticofugal terminal topography from the medial S1 cortex.
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2014.05.039