Substance P is associated with hypothalamic paraventricular nucleus activation that coincides with increased urotensin 2 mRNA in chicks

Highlights • Chicks intracerebroventricularly (ICV) injected with substance P reduced food intake. • Substance P injection was associated with paraventricular nucleus activation. • Substance P injection was associated with increased mRNA for urotensin 2 in the paraventricular nucleus.

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Bibliographische Detailangaben
Veröffentlicht in:	Neuropeptides (Edinburgh) 2014-10, Vol.48 (5), p.305-311
Hauptverfasser:	Mace, Jacob D, Tachibana, Tetsuya, Wang, Guoqing, Newmyer, Brandon A, Guilliams, Evin, Gilbert, Elizabeth R, Cline, Mark A
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Anorexia - chemically induced Anorexia - metabolism Appetite Depressants - pharmacology Chick Chickens Diencephalon - drug effects Diencephalon - metabolism Disease Models, Animal Drinking - drug effects Eating - drug effects Endocrinology & Metabolism Female Hypothalamus Infusions, Intraventricular Male Paraventricular Hypothalamic Nucleus - drug effects Paraventricular Hypothalamic Nucleus - metabolism Paraventricular nucleus RNA, Messenger - metabolism Substance P Substance P - administration & dosage Substance P - pharmacology Urotensin Urotensins - metabolism
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Beschreibung
Zusammenfassung:	Highlights • Chicks intracerebroventricularly (ICV) injected with substance P reduced food intake. • Substance P injection was associated with paraventricular nucleus activation. • Substance P injection was associated with increased mRNA for urotensin 2 in the paraventricular nucleus.
ISSN:	0143-4179 1532-2785
DOI:	10.1016/j.npep.2014.06.001