Rat platelet phospholipase A sub(2). Kinetic characterization using the monomolecular film technique

Rat platelet phospholipase A sub(2). Kinetic characterization using the monomolecular film technique

We have determined some kinetic parameters of rat platelet phospholipase A sub(2), such as surface pressure dependency and substrate specificity, using the monomolecular film technique. We found that rat platelet phospholipase A sub(2) is very specific for phospholipids having a negatively charged h...

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Veröffentlicht in:European journal of biochemistry 1992-01, Vol.204 (2), p.793-797
Hauptverfasser: Ransac, S, Aarsman, J, van den Bosch, H, Gancet, C, de Haas, GH, Verger, R
Format: Artikel
Sprache:eng
Schlagworte:
incorporation
kinetics
monolayers
phospholipase A2
platelets
rats
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Zusammenfassung:We have determined some kinetic parameters of rat platelet phospholipase A sub(2), such as surface pressure dependency and substrate specificity, using the monomolecular film technique. We found that rat platelet phospholipase A sub(2) is very specific for phospholipids having a negatively charged headgroup, no activity was detected when using zwitterionic phospholipids such as phosphatidylcholine.
ISSN:0014-2956