Fetal Growth Restriction Is Worse than Extreme Prematurity for the Developing Lung

Background: Perinatal lung growth is highly vulnerable to inflammation and intrauterine growth restriction (IUGR), two major risk factors for chronic lung disease (CLD) in preterm neonates. However, the balance between extremely low gestational age (ELGA) and IUGR in very preterm infants as risk fac...

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Veröffentlicht in:	Neonatology (Basel, Switzerland) Switzerland), 2014-01, Vol.106 (4), p.304-310
Hauptverfasser:	Soudée, Sophie, Vuillemin, Lucie, Alberti, Corinne, Mohamed, Damir, Becquet, Odile, Farnoux, Caroline, Biran, Valérie, Baud, Olivier
Format:	Artikel
Sprache:	eng
Schlagworte:	Birth Weight Child Development Chronic Disease Female Fetal Growth Retardation - mortality Fetal Growth Retardation - physiopathology Gestational Age Hospital Mortality Humans Infant Infant Mortality Infant, Extremely Premature Infant, Newborn Lung - growth & development Lung Diseases - diagnosis Lung Diseases - mortality Lung Diseases - physiopathology Lung Diseases - therapy Male Original Paper Oxygen Inhalation Therapy Paris Respiration, Artificial Retrospective Studies Risk Assessment Risk Factors
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Zusammenfassung:	Background: Perinatal lung growth is highly vulnerable to inflammation and intrauterine growth restriction (IUGR), two major risk factors for chronic lung disease (CLD) in preterm neonates. However, the balance between extremely low gestational age (ELGA) and IUGR in very preterm infants as risk factors for CLD and co-morbidities remains poorly explored. Objectives: This single-center study aims to compare neonatal morbidity (including CLD) and mortality among ELGA infants with normal birth weight (ELGA-AGA), very preterm infants with IUGR
ISSN:	1661-7800 1661-7819
DOI:	10.1159/000360842