Thyroid hormone regulation of hepatic lipid and carbohydrate metabolism

Thyroid hormone regulation of hepatic lipid and carbohydrate metabolism

Highlights • Thyroid hormone induces hepatic lipogenesis and lipophagy. • Thyroid hormone increases reverse cholesterol transport. • Thyroid hormone regulates hepatic gluconeogenesis via SirT1 and FoxO1.

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Bibliographische Detailangaben
Veröffentlicht in:Trends in endocrinology and metabolism 2014-10, Vol.25 (10), p.538-545
Hauptverfasser: Sinha, Rohit A, Singh, Brijesh K, Yen, Paul M
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Carbohydrate Metabolism - physiology
Endocrinology & Metabolism
glucose metabolism
Homeostasis
Humans
lipid metabolism
Lipid Metabolism - physiology
liver
Liver - metabolism
Liver Diseases - metabolism
thyroid hormone
Thyroid Hormones - physiology
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Beschreibung
Zusammenfassung:Highlights • Thyroid hormone induces hepatic lipogenesis and lipophagy. • Thyroid hormone increases reverse cholesterol transport. • Thyroid hormone regulates hepatic gluconeogenesis via SirT1 and FoxO1.
ISSN:1043-2760
1879-3061
DOI:10.1016/j.tem.2014.07.001