An Elegant Microwave Assisted One-Pot Synthesis of Di(α-aminophosphonate) Pesticides

A new class of di(α‐aminophosphonate) pesticides were prepared by the Kabachnik–Fields reaction under solvent‐ and catalyst‐free conditions with microwave irradiation, and the products were obtained in good‐to‐excellent yields at shorter reaction time. These compounds were characterized by IR, 1H, 13C, 31P NMR, and mass spectral data. Among them, compounds 4f, 4c, and 4h showed good pesticidal activity against Spodoptera litura, with 92.6, 91.3, and 89.3% mortality. New di(α‐aminophosphonate) derivatives with pesticidal activity were prepared by Kabachnik–Fields reaction under solvent‐ and catalyst‐free conditions using microwave irradiation. Among all the compounds, 4f, 4c, and 4h exhibited good activity against Spodoptera litura, with 92.6, 91.3, and 89.3% mortality.