A case of bilateral rheumatoid pleuritis successfully treated with tocilizumab

Abstract The patient was a 77-year-old woman diagnosed as having rheumatoid arthritis (RA) in 1973. She was initiated on infliximab therapy in addition to methotrexate administration in 2009. The therapeutic response decreased after the fifth dose of infliximab, and the patient developed rheumatoid...

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Veröffentlicht in:	Modern rheumatology 2014-11, Vol.24 (6), p.1001-1004
Hauptverfasser:	Ohtsuka, Keiko, Takeuchi, Kimihiko, Matsushita, Masatoshi, Aramaki, Tetsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antibodies, Monoclonal, Humanized - therapeutic use Antirheumatic Agents - therapeutic use Arthritis, Rheumatoid - complications Arthritis, Rheumatoid - drug therapy Drug therapy Female Humans Pleurisy - drug therapy Pleurisy - etiology Prescription drugs Rheumatoid arthritis Success Treatment Outcome
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Zusammenfassung:	Abstract The patient was a 77-year-old woman diagnosed as having rheumatoid arthritis (RA) in 1973. She was initiated on infliximab therapy in addition to methotrexate administration in 2009. The therapeutic response decreased after the fifth dose of infliximab, and the patient developed rheumatoid pleuritis due to increased RA disease activity. The therapy was switched from infliximab to tocilizumab, which resulted in amelioration of the arthralgias well as pleuritis. Our results suggest that tocilizumab is an effective treatment alternative for the treatment of rheumatoid pleuritis.
ISSN:	1439-7595 1439-7609
DOI:	10.3109/14397595.2013.874745