Virus Meets Host MicroRNA: the Destroyer, the Booster, the Hijacker

Virus Meets Host MicroRNA: the Destroyer, the Booster, the Hijacker

Virus-host interactions highlight key regulatory steps in the control of gene expression. MicroRNAs (miRNAs) are small noncoding RNAs that regulate protein production via base pairing with mRNAs. Both DNA and RNA viruses have evolved mechanisms to degrade, boost, or hijack cellular miRNAs to benefit...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Molecular and cellular biology 2014-10, Vol.34 (20), p.3780-3787
Hauptverfasser: Guo, Yang Eric, Steitz, Joan A.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Base Sequence
Encephalitis Virus, Eastern Equine - physiology
Gene Expression Regulation, Viral
Herpesviridae - physiology
Host-Pathogen Interactions
Humans
MicroRNAs - genetics
MicroRNAs - metabolism
Minireview
Poxviridae - physiology
RNA Interference
RNA Stability
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Virus-host interactions highlight key regulatory steps in the control of gene expression. MicroRNAs (miRNAs) are small noncoding RNAs that regulate protein production via base pairing with mRNAs. Both DNA and RNA viruses have evolved mechanisms to degrade, boost, or hijack cellular miRNAs to benefit the viral life cycle. This minireview focuses on recent discoveries in virus-host miRNA interactions.
ISSN:1098-5549
0270-7306
1098-5549
DOI:10.1128/MCB.00871-14