Is there a role for cyclosporine in asthma?

CsA, as discussed in this review, affects inflammatory cells and their mediators. Its effects appear to exceed those effects induced by other anti-inflammatory agents and suggest its probable usefulness in the management of severe steroid-dependent asthma. Mechanisms of the action of CsA have been r...

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Veröffentlicht in:Journal of allergy and clinical immunology 1992-02, Vol.89 (2), p.629-636
Hauptverfasser: Calderón, Eduardo, Lockey, Richard F., Bukantz, Samuel C., Coffey, Ronald G., Ledford, Dennis K.
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container_end_page 636
container_issue 2
container_start_page 629
container_title Journal of allergy and clinical immunology
container_volume 89
creator Calderón, Eduardo
Lockey, Richard F.
Bukantz, Samuel C.
Coffey, Ronald G.
Ledford, Dennis K.
description CsA, as discussed in this review, affects inflammatory cells and their mediators. Its effects appear to exceed those effects induced by other anti-inflammatory agents and suggest its probable usefulness in the management of severe steroid-dependent asthma. Mechanisms of the action of CsA have been reviewed with that objective in mind.
doi_str_mv 10.1016/0091-6749(92)90331-U
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source MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects Asthma - drug therapy
Asthma - etiology
Asthma - physiopathology
Biological and medical sciences
Cyclosporine - adverse effects
Cyclosporine - pharmacokinetics
Cyclosporine - pharmacology
Cyclosporine - therapeutic use
Depression, Chemical
Dose-Response Relationship, Drug
Humans
Immunomodulators
Medical sciences
Pharmacology. Drug treatments
title Is there a role for cyclosporine in asthma?
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