On the safety of Bacillus subtilis and B. amyloliquefaciens : a review

An overwhelming majority of recombinant microorganisms to be used by industry are expected to be based on harmless hosts. Many of these have been proven safe over many years of experience in industrial settings. Furthermore, extensive information on the incapacity to cause disease, i.e. non-pathogen...

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Veröffentlicht in:Applied microbiology and biotechnology 1991-10, Vol.36 (1), p.1-4
Hauptverfasser: SIETSKE DE BOER, A, DIDERICHSEN, B
Format: Artikel
Sprache:eng
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Zusammenfassung:An overwhelming majority of recombinant microorganisms to be used by industry are expected to be based on harmless hosts. Many of these have been proven safe over many years of experience in industrial settings. Furthermore, extensive information on the incapacity to cause disease, i.e. non-pathogenic and non-toxicogenic potential, of some of these organisms can be found in the literature. We believe that a review of the literature and present experience with some of these host organisms will be useful for assessment of the safety of many recombinant organisms.
ISSN:0175-7598
1432-0614
DOI:10.1007/bf00164689