Immobilization and Culture of Cells

We have studied and applied the immobilization technique by the radiation polymerization method to the fixation and controlled release of biofunctional components. This method is a physical entrapment under broad conditions with widely variable polymeric materials and is especially suitably for the uses of controlled release of biofunctional molecules and of enhanced fixation and culture of cells. In this report, some results of studies on the relationship between the type of cells, the structure and properties of the polymeric support, and the enhanced effects in the cell culture in the immobilized state are described. The immobilization and cell culture of Saccharomyces formosessis as an ethanol fermentation yeast and of Trichoderma reesei and Sporotrichum cellulophilum as cellulase-producing fungi was studied.