Biosynthesis of vitamin B sub(12) in Pseudomonas denitrificans : The biosynthetic sequence from precorrin-6y to precorrin-8x is catalyzed by the cobL gene product

Biosynthesis of vitamin B sub(12) in Pseudomonas denitrificans : The biosynthetic sequence from precorrin-6y to precorrin-8x is catalyzed by the cobL gene product

A protein catalyzing methylation at C-5 and C-15 and decarboxylation of the acetic acid side chain at C-12 on precorrin-6y to yield precorrin-8x was purified to homogeneity from a recombinant strain of Pseudomonas denitrificans . It was sequenced at the N terminus and shown to be encoded by the cobL...

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Veröffentlicht in:Journal of bacteriology 1992-01, Vol.174 (3), p.1050-1052
Hauptverfasser: Blanche, F, Famechon, A, Thibaut, D, Debussche, L, Cameron, B, Crouzet, J
Format: Artikel
Sprache:eng
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Zusammenfassung:A protein catalyzing methylation at C-5 and C-15 and decarboxylation of the acetic acid side chain at C-12 on precorrin-6y to yield precorrin-8x was purified to homogeneity from a recombinant strain of Pseudomonas denitrificans . It was sequenced at the N terminus and shown to be encoded by the cobL gene.
ISSN:0021-9193