Mechanisms of immunotoxicity to isocyanates

This review focuses on mechanisms of isocyanate sensitivity. It evaluates information obtained from animal models as well as clinical studies and highlights toxicologic concepts derived from investigations of isocyanate sensitization. Lastly, it explores possible reasons for the current controversy...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chemical research in toxicology 1991-09, Vol.4 (5), p.503-509
Hauptverfasser:	Karol, Meryl H, Jin, Ruzhi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Asthma - immunology Asthma - physiopathology Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Cyanates - immunology Cyanates - toxicity Humans Hypersensitivity - immunology Hypersensitivity - physiopathology Immunity - drug effects Medical sciences Toluene 2,4-Diisocyanate - immunology Toluene 2,4-Diisocyanate - toxicity Toxicology Various organic compounds
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	This review focuses on mechanisms of isocyanate sensitivity. It evaluates information obtained from animal models as well as clinical studies and highlights toxicologic concepts derived from investigations of isocyanate sensitization. Lastly, it explores possible reasons for the current controversy surrounding the pathogenesis of isocyanate sensitization.
ISSN:	0893-228X 1520-5010
DOI:	10.1021/tx00023a001