Further evidence for the importance of parental source of the Xce allele in X chromosome inactivation

Using mice that were mosaics for both Xce and phosphoglycerate kinase (Pgk-1) alleles, we present further evidence that the parental source of the X chromosome may affect the probability of that X chromosome remaining active. The reciprocal cross differences in PGK-1 activity described here are inte...

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Veröffentlicht in:Genetical Research 1991-08, Vol.58 (1), p.63-65
Hauptverfasser: Fowlis, Deborah J., Ansell, John D., Micklem, H. Spedding
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Sprache:eng
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Zusammenfassung:Using mice that were mosaics for both Xce and phosphoglycerate kinase (Pgk-1) alleles, we present further evidence that the parental source of the X chromosome may affect the probability of that X chromosome remaining active. The reciprocal cross differences in PGK-1 activity described here are intermediate between those published previously for other alleles of Xce.
ISSN:0016-6723
1469-5073
DOI:10.1017/S001667230002961X