Identification of (Na,K)ATPase inhibitor in brine shrimp, Artemia salina, as long-chain fatty acids

Identification of (Na,K)ATPase inhibitor in brine shrimp, Artemia salina, as long-chain fatty acids

An inhibitory activity to (Na,K)ATPase was found in cell extracts of the brine shrimp, Artemia salina , irrespective of its developmental stages. Organic solvent extraction together with gas chromatographic analysis reveals that the inhibitory activity is due to long-chain, non-esterified fatty acid...

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Veröffentlicht in:Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology Biochemical, systemic, and environmental physiology, 1991-03, Vol.161 (1), p.69-72
Hauptverfasser: MOROHASHI, M, TSUCHIYA, K, MITA, T, KAWAMURA, M
Format: Artikel
Sprache:eng
Schlagworte:
Artemia salina
Biochemistry. Physiology. Immunology
Biological and medical sciences
Brackish
Crustacea
Fundamental and applied biological sciences. Psychology
Invertebrates
Physiology. Development
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Zusammenfassung:An inhibitory activity to (Na,K)ATPase was found in cell extracts of the brine shrimp, Artemia salina , irrespective of its developmental stages. Organic solvent extraction together with gas chromatographic analysis reveals that the inhibitory activity is due to long-chain, non-esterified fatty acids and their derivatives. Unsaturated fatty acids, especially with cis-configuration, are more effective in inhibition than saturated ones.
ISSN:0174-1578
1432-136X
DOI:10.1007/BF00258748