Kojistatin A, a New Cysteine Protease Inhibitor Produced by Aspergillus oryzae

A new cysteine protease inhibitor, named kojistatin A, was found in the extract of a solid culture of Aspergillus oryzae ATCC 20386. The structure of kojistatin A was determined on the basis of chemical and spectroscopic evidence. Kojistatin A specifically inhibited cysteine proteases such as papain...

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Veröffentlicht in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 1996, Vol.60 (10), p.1747-1748
Hauptverfasser: Sato, Nobuyoshi, Horiuchi, Tatsuo, Hamano, Mitsutoshi, Sekine, Hiroshi, Chiba, Satoru, Yamamoto, Hiroki, Yoshioka, Takeya, Kimura, Ikuo, Satake, Mikio, Ida, Yoshiteru
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container_end_page 1748
container_issue 10
container_start_page 1747
container_title Bioscience, biotechnology, and biochemistry
container_volume 60
creator Sato, Nobuyoshi
Horiuchi, Tatsuo
Hamano, Mitsutoshi
Sekine, Hiroshi
Chiba, Satoru
Yamamoto, Hiroki
Yoshioka, Takeya
Kimura, Ikuo
Satake, Mikio
Ida, Yoshiteru
description A new cysteine protease inhibitor, named kojistatin A, was found in the extract of a solid culture of Aspergillus oryzae ATCC 20386. The structure of kojistatin A was determined on the basis of chemical and spectroscopic evidence. Kojistatin A specifically inhibited cysteine proteases such as papain, ficin, and bromelain.
doi_str_mv 10.1271/bbb.60.1747
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source Oxford University Press Journals All Titles (1996-Current); J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; Open Access Titles of Japan; EZB-FREE-00999 freely available EZB journals; Free Full-Text Journals in Chemistry
subjects Aspergillus oryzae
Biological and medical sciences
Biology of microorganisms of confirmed or potential industrial interest
Biotechnology
cysteine protease inhibitor
Fundamental and applied biological sciences. Psychology
kojistatin A
Mission oriented research
Physiology and metabolism
title Kojistatin A, a New Cysteine Protease Inhibitor Produced by Aspergillus oryzae
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