Kojistatin A, a New Cysteine Protease Inhibitor Produced by Aspergillus oryzae

A new cysteine protease inhibitor, named kojistatin A, was found in the extract of a solid culture of Aspergillus oryzae ATCC 20386. The structure of kojistatin A was determined on the basis of chemical and spectroscopic evidence. Kojistatin A specifically inhibited cysteine proteases such as papain...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 1996, Vol.60 (10), p.1747-1748
Hauptverfasser:	Sato, Nobuyoshi, Horiuchi, Tatsuo, Hamano, Mitsutoshi, Sekine, Hiroshi, Chiba, Satoru, Yamamoto, Hiroki, Yoshioka, Takeya, Kimura, Ikuo, Satake, Mikio, Ida, Yoshiteru
Format:	Artikel
Sprache:	eng
Schlagworte:	Aspergillus oryzae Biological and medical sciences Biology of microorganisms of confirmed or potential industrial interest Biotechnology cysteine protease inhibitor Fundamental and applied biological sciences. Psychology kojistatin A Mission oriented research Physiology and metabolism
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Beschreibung
Zusammenfassung:	A new cysteine protease inhibitor, named kojistatin A, was found in the extract of a solid culture of Aspergillus oryzae ATCC 20386. The structure of kojistatin A was determined on the basis of chemical and spectroscopic evidence. Kojistatin A specifically inhibited cysteine proteases such as papain, ficin, and bromelain.
ISSN:	0916-8451 1347-6947
DOI:	10.1271/bbb.60.1747