Mechanistic studies in man, laboratory animals and in vitro systems

Mechanistic studies in man, laboratory animals and in vitro systems

This paper discusses the mechanisms at the functional and molecular levels by which chemicals exert their toxic effects on living organisms. Attention is centred on issues relevant to human health, and is therefore mainly devoted to studies applicable to the safety evaluation of food, pharmaceutical...

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Veröffentlicht in:Food and chemical toxicology 1990, Vol.28 (11), p.767-770
1. Verfasser: Schou, J.S.
Format: Artikel
Sprache:eng
Schlagworte:
animal experimentation
Animals
Biological and medical sciences
Carcinogens - toxicity
Cell Line
food chemistry
Food toxicology
foods
guidelines
histopathology
Humans
Immunity - drug effects
immunology
in vitro
Medical sciences
neoplasms
Organ Specificity
teratogens
Teratogens - toxicity
testing
toxicity
Toxicology
Toxicology - methods
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Beschreibung
Zusammenfassung:This paper discusses the mechanisms at the functional and molecular levels by which chemicals exert their toxic effects on living organisms. Attention is centred on issues relevant to human health, and is therefore mainly devoted to studies applicable to the safety evaluation of food, pharmaceuticals, cosmetics, pesticides, and other chemicals to which man is directly exposed.
ISSN:0278-6915
1873-6351
DOI:10.1016/0278-6915(90)90076-Y