Functions of the various human IgG Fc receptors in mediating killing of Toxoplasma gondii

Functions of the various human IgG Fc receptors in mediating killing of Toxoplasma gondii

The three types of IgG FcR (Fc gamma RI, Fc gamma RII, Fc gamma RIII) on human leukocytes play an important role in elimination of antibody-coated infectious agents. To further understand the role of the different Fc gamma R in mediating this killing, we examined the ability of human myeloid and lym...

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Veröffentlicht in:The Journal of immunology (1950) 1991-05, Vol.146 (9), p.3145-3151
Hauptverfasser: Erbe, D V, Pfefferkorn, E R, Fanger, M W
Format: Artikel
Sprache:eng
Schlagworte:
Toxoplasma gondii
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Zusammenfassung:The three types of IgG FcR (Fc gamma RI, Fc gamma RII, Fc gamma RIII) on human leukocytes play an important role in elimination of antibody-coated infectious agents. To further understand the role of the different Fc gamma R in mediating this killing, we examined the ability of human myeloid and lymphoid cells to kill the protozoan Toxoplasma gondii in the presence of anti-Toxoplasma IgG or bispecific antibodies.
ISSN:0022-1767