Studies on New Antitumor Antibiotics, Leptofuranins A, B, C and D: II. Physicochemical Properties and Structure Elucidation
The structures of new antitumor antibiotics, leptofuranins A, B, C and D were elucidated to be as shown in Fig. 1 by NMR spectral analysis including a variety of two-dimensional techniques. The leptofuranins are novel leptomycin-related substances containing a tetrahydrofuran ring. Leptofuranins C a...
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| Veröffentlicht in: | Journal of antibiotics 1996/10/25, Vol.49(10), pp.980-984 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | The structures of new antitumor antibiotics, leptofuranins A, B, C and D were elucidated to be as shown in Fig. 1 by NMR spectral analysis including a variety of two-dimensional techniques. The leptofuranins are novel leptomycin-related substances containing a tetrahydrofuran ring. Leptofuranins C and D were revealed to be in tautomeric isomerism and their relative stereochemistries were analyzed by NOESY experiments. |
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| ISSN: | 0021-8820 1881-1469 |
| DOI: | 10.7164/antibiotics.49.980 |