Poloxamer 407 as a bacterial abhesive for hydrogel contact lenses

Poloxamer 407 as a bacterial abhesive for hydrogel contact lenses

Bacterial adherence and colonization of biomedical prosthetic implants is one of the main causes for implant withdrawal. The abhesive (anti‐adhesive) effect of poloxamer 407 on several Gram‐positive and Gramnegative strains and the site of action of its effect have been investigated. Poloxamer 407 s...

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Veröffentlicht in:Journal of biomedical materials research 1994-03, Vol.28 (3), p.303-309
Hauptverfasser: Portolés, Marta, Refojo, Miguel F., Leong, Fee-Lai
Format: Artikel
Sprache:eng
Schlagworte:
Pseudomonas aeruginosa
Staphylococcus
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Zusammenfassung:Bacterial adherence and colonization of biomedical prosthetic implants is one of the main causes for implant withdrawal. The abhesive (anti‐adhesive) effect of poloxamer 407 on several Gram‐positive and Gramnegative strains and the site of action of its effect have been investigated. Poloxamer 407 significantly inhibited 92–99% of Pseudomonas aeruginosa adherence to hydrophilic contact lenses (P
ISSN:0021-9304
1097-4636
DOI:10.1002/jbm.820280304