Evaluation of Antimicrobial Pigment Produced by Streptomyces coeruleorubidus

The bacterial pigments are secondary metabolites that help the producer to survive in different environments. The bacterial pigments have shown different properties such as antitumor, anticancer and antimicrobial effects. The present study was conducted to isolate soil origin Actinomycetes and to evaluate their antimicrobial pigments. In total, eighty seven soil samples were collected from different areas in Kazeroun City, Iran. The samples were serially diluted and 0.1 mL of each dilution was streaked on SCA and ISP2 media and incubated at 30C° for 5 days. Then, pigmented Actinomycetes were selected and subjected for propagation and pigment extraction using different solvents. To continue the experiments, the antimicrobial property of each pigment was evaluated against Staphylococcus aureus, Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa, Shigella dysentriae, Citrobacter ferundii, Klebsiella peumoniae, Serratia marcecens, Aspergillus sp. and Candida albicans. Overall, soil origin Actinomycetes could produce pigments with antimicrobial property. Therefore, Actinomycetes pigments must be considered a special remedy for investigation in order to eliminate occurrence of antibiotic resistant microorganisms.