Gastrointestinal cancers: Influence of gut microbiota, probiotics and prebiotics

Highlights • Gut microbiota is a key element for gastrointestinal cancers (especially of the colon and stomach) • Carcinogenesis may be induced by gut microbiota through complex and various mechanisms • Probiotics and prebiotics have anticarcinogenic effects, mainly in vitro and in animal studies •...

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Veröffentlicht in:	Cancer letters 2014-04, Vol.345 (2), p.258-270
1. Verfasser:	Serban, Daniela Elena
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria Cell growth Colon Colorectal cancer Diarrhea Disease Disease prevention Dysbiosis Dysbiosis - complications Dysbiosis - microbiology Dysbiosis - therapy Enzymes Gastroesophageal reflux Gastrointestinal cancer Gastrointestinal Neoplasms - microbiology Gastrointestinal Neoplasms - prevention & control Genomes Gut microflora Hematology, Oncology and Palliative Medicine Humans Intestines - microbiology Lymphoma Microorganisms Prebiotics Probiotics Probiotics - therapeutic use Proteins Quality of life Small intestine Studies Surgery Treatment Outcome
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Beschreibung
Zusammenfassung:	Highlights • Gut microbiota is a key element for gastrointestinal cancers (especially of the colon and stomach) • Carcinogenesis may be induced by gut microbiota through complex and various mechanisms • Probiotics and prebiotics have anticarcinogenic effects, mainly in vitro and in animal studies • In human GI cancers, probiotics and prebiotics are promising tools in prevention and/or therapy.
ISSN:	0304-3835 1872-7980
DOI:	10.1016/j.canlet.2013.08.013