Invasive fungal infections in solid organ transplant recipients

Solid organ transplant (SOT) recipients have a significant risk of invasive fungal diseases (IFD) caused mainly by Candida spp. and Aspergillus spp. Candida spp. is the most frequent agent of IFD in the transplant recipient. The absence of clinical trials and the epidemiological differences in IFD i...

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Veröffentlicht in:	Clinical microbiology and infection 2014-09, Vol.20 (s7), p.27-48
Hauptverfasser:	Gavaldà, J., Meije, Y., Fortún, J., Roilides, E., Saliba, F., Lortholary, O., Muñoz, P., Grossi, P., Cuenca-Estrella, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aspergillus Blood & organ donations Candida Candidiasis, Invasive - diagnosis Candidiasis, Invasive - epidemiology Candidiasis, Invasive - prevention & control Candidiasis, Invasive - therapy Drug interactions Humans Immunocompromised Host Immunosuppressive Agents - therapeutic use invasive aspergillosis invasive candidiasis Invasive Pulmonary Aspergillosis - diagnosis Invasive Pulmonary Aspergillosis - epidemiology Invasive Pulmonary Aspergillosis - prevention & control Invasive Pulmonary Aspergillosis - therapy Opportunistic Infections - diagnosis Opportunistic Infections - epidemiology Opportunistic Infections - prevention & control Opportunistic Infections - therapy Organ Transplantation solid organ transplantation Transplant infectious disease Transplant Recipients Transplants & implants
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Beschreibung
Zusammenfassung:	Solid organ transplant (SOT) recipients have a significant risk of invasive fungal diseases (IFD) caused mainly by Candida spp. and Aspergillus spp. Candida spp. is the most frequent agent of IFD in the transplant recipient. The absence of clinical trials and the epidemiological differences in IFD in different transplant programmes mean that there are no definitive recommendations for the diagnosis, treatment and prevention of IFD in SOT, so most of the evidence must be based on clinical experience.
ISSN:	1198-743X 1469-0691
DOI:	10.1111/1469-0691.12660