Evidence of Selection During HIV-1 Transmission in Heterosexual Couples in Zambia

Evidence of Selection During HIV-1 Transmission in Heterosexual Couples in Zambia

Background: HIV infection occurs by the transmission of one or a few of the variants present in the donor. This process is poorly understood and it is not known if this transmission bottleneck is mediated by an active selection process or is the consequence of a random event.

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Bibliographische Detailangaben
Veröffentlicht in:AIDS research and human retroviruses 2013-11, Vol.29 (11), p.A-78
Hauptverfasser: Monaco, D C, Carlson, J, Schaeffer, M, Claiborne, D, Prince, J, Dilernia, D, Denis, K, Kilembe, W, Lakhi, S, Tang, J, Farmer, P, Kaslow, R, Allen, S, Goepfert, P, Heckerman, D, Hunter, E
Format: Artikel
Sprache:eng
Schlagworte:
Human immunodeficiency virus 1
Retrovirus
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Zusammenfassung:Background: HIV infection occurs by the transmission of one or a few of the variants present in the donor. This process is poorly understood and it is not known if this transmission bottleneck is mediated by an active selection process or is the consequence of a random event.
ISSN:0889-2229