HIV Antibodies Catch Infectious Particles Independently of Their Neutralising Profiles

HIV Antibodies Catch Infectious Particles Independently of Their Neutralising Profiles

Background: Formation of antibody/virus immune complexes has been proposed to decrease the number of virus accessible to target cells, limiting virus infectivity. Therefore, anti-HIV specific antibodies (Abs) able to bind HIV infectious particles may be particularly relevant at the mucosal site, to...

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Veröffentlicht in:AIDS research and human retroviruses 2013-11, Vol.29 (11), p.A-51
Hauptverfasser: Lambotin, M, Laumond, G, Schmidt, S, Decoville, T, Peressin, M, Su, B, Biedma, M E, Proust, A, Moog, C
Format: Artikel
Sprache:eng
Schlagworte:
Human immunodeficiency virus
Retrovirus
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Zusammenfassung:Background: Formation of antibody/virus immune complexes has been proposed to decrease the number of virus accessible to target cells, limiting virus infectivity. Therefore, anti-HIV specific antibodies (Abs) able to bind HIV infectious particles may be particularly relevant at the mucosal site, to participate in HIV protection.
ISSN:0889-2229