PACAP and PAC1 receptor in the reproductive cycle of male lizard Podarcis sicula

Highlights • In Podarcis, PACAP is synthesized directly in the testis in all reproductive cycle. • In Podarcis testis, PACAP mRNA concentration show a specific expression pathway during the reproductive cycle. • PACAP and PAC1 receptor are widely distributed in Podarcis testis during the reproductiv...

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Veröffentlicht in:	General and comparative endocrinology 2014-09, Vol.205, p.102-108
Hauptverfasser:	Rosati, Luigi, Prisco, Marina, Coraggio, Francesca, Valiante, Salvatore, Scudiero, Rosaria, Laforgia, Vincenza, Andreuccetti, Piero, Agnese, Marisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Endocrinology & Metabolism Humans Lizards - physiology Male PAC1R PACAP Pituitary Adenylate Cyclase-Activating Polypeptide - genetics Pituitary Adenylate Cyclase-Activating Polypeptide - metabolism Podarcis sicula Real-Time Polymerase Chain Reaction Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - genetics Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I - metabolism Reproduction Reproductive cycle RNA, Messenger - genetics RNA, Messenger - metabolism Spermatogenesis Testis - cytology Testis - metabolism
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Zusammenfassung:	Highlights • In Podarcis, PACAP is synthesized directly in the testis in all reproductive cycle. • In Podarcis testis, PACAP mRNA concentration show a specific expression pathway during the reproductive cycle. • PACAP and PAC1 receptor are widely distributed in Podarcis testis during the reproductive cycle. • In Podarcis, PACAP probably influences spermatogenesis and steroidogenesis.
ISSN:	0016-6480 1095-6840
DOI:	10.1016/j.ygcen.2014.05.009