Total Synthesis of (±)-Phosphonothrixin, a Novel Herbicidal Antibiotic Containing C-P Bond

Phosphonothrixin (1) is a novel herbicidal agent produced by Saccharothrix sp. ST-888, with a unique structure possessing a C-P bond and an isoprene unit. The total synthesis of this antibiotic was accomplished from methyl (bromomethyl)acrylate in six steps.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of antibiotics 1995/10/25, Vol.48(10), pp.1134-1137
Hauptverfasser:	NAKAMURA, KAZUHIKO, KIMURA, TAKASHI, KANNO, HISASHI, TAKAHASHI, EISAKU
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemical synthesis Biological and medical sciences Chemical control Fundamental and applied biological sciences. Psychology Herbicides - chemical synthesis Organophosphonates - chemical synthesis Parasitic plants. Weeds Phytopathology. Animal pests. Plant and forest protection Saccharothrix Structure-Activity Relationship Weeds
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Phosphonothrixin (1) is a novel herbicidal agent produced by Saccharothrix sp. ST-888, with a unique structure possessing a C-P bond and an isoprene unit. The total synthesis of this antibiotic was accomplished from methyl (bromomethyl)acrylate in six steps.
ISSN:	0021-8820 1881-1469
DOI:	10.7164/antibiotics.48.1134