Who Really Benefits From Nephron-sparing Surgery?

Objective To analyze the influence of preoperative renal function on postoperative renal outcomes after radical nephrectomy (RN) and nephron-sparing surgery (NSS) for malignancy in patients stratified according to preoperative chronic kidney disease (CKD) stage and surgical extent (NSS vs RN). Patients and Methods Retrospective review of patients undergoing renal surgery for localized renal masses stratified by surgical extent and preoperative CKD stage based on glomerular filtration rate (GFR) level: stage I (>90 mL/min/1.73 m2 ), stage II (60-89 mL/min/1.73 m2 ), and stage III (30-59 mL/min/1.73 m2 ). Survival analysis for significant renal impairment was based on freedom from the development of new-onset GFR