Synchronous lobular carcinoma in situ and invasive lobular cancer: Marker or precursor for invasive lobular carcinoma

Abstract Aim Lobular carcinoma in situ (LCIS) is a known risk factor for invasive breast carcinoma, but there is increasing data indicating a possible precursor relationship. This study investigates the incidence of lobular carcinoma in situ that occurs with invasive lobular carcinoma (ILC). Methods...

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Veröffentlicht in:	European journal of surgical oncology 2014-10, Vol.40 (10), p.1245-1249
Hauptverfasser:	Wallace, A.S, Xiang, D, Hockman, L, Arya, M, Jeffress, J, Wang, Z, Dale, P.S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Breast Breast Neoplasms - pathology Breast Neoplasms - surgery Carcinoma in Situ - pathology Carcinoma in Situ - surgery Carcinoma, Lobular - pathology Carcinoma, Lobular - surgery Cohort Studies Disease Progression Female Hematology, Oncology and Palliative Medicine Humans Lobular carcinoma Lobular carcinoma in situ Mastectomy Mastectomy, Segmental Middle Aged Neoplasms, Multiple Primary - pathology Neoplasms, Multiple Primary - surgery Outcome Precursor Retrospective Studies Surgery
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Zusammenfassung:	Abstract Aim Lobular carcinoma in situ (LCIS) is a known risk factor for invasive breast carcinoma, but there is increasing data indicating a possible precursor relationship. This study investigates the incidence of lobular carcinoma in situ that occurs with invasive lobular carcinoma (ILC). Methods Women diagnosed with ILC or LCIS from 2000 to 2010 were retrospectively identified and reviewed after institutional review board approval. This group was divided into two cohorts: ILC alone, and LCIS and ILC (ILC/LCIS). Patient demographics, disease characteristics, and treatment modalities were captured. p
ISSN:	0748-7983 1532-2157
DOI:	10.1016/j.ejso.2014.04.007