Portulaca oleracea extracts protect human keratinocytes and fibroblasts from UV-induced apoptosis

Portulaca oleracea extracts, known as Ma Chi Hyun in the traditional Korean medicine, show a variety of biomedical efficacies including those in anti‐inflammation and anti‐allergy. In this study, we investigate the protective activity of the P. oleracea extracts against UVB‐induced damage in human e...

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Veröffentlicht in:	Experimental dermatology 2014-10, Vol.23 (s1), p.13-17
Hauptverfasser:	Lee, Suyeon, Kim, Ki Ho, Park, Changhoon, Lee, Jong-Suk, Kim, Young Heui
Format:	Artikel
Sprache:	eng
Schlagworte:	Annexin A5 - metabolism apoptosis Apoptosis - drug effects Apoptosis - radiation effects Cell Survival - drug effects Cell Survival - radiation effects Cells, Cultured DNA Fragmentation fibroblast Fibroblasts - cytology Fibroblasts - drug effects Fibroblasts - radiation effects Fluorescein-5-isothiocyanate - analogs & derivatives Fluorescein-5-isothiocyanate - metabolism Humans keratinocyte Keratinocytes - drug effects Keratinocytes - pathology Keratinocytes - radiation effects Medicine, Korean Traditional Phosphatidylserines - metabolism Plant Extracts - pharmacology Portulaca Portulaca oleracea extracts Radiation-Protective Agents - pharmacology Ultraviolet Rays - adverse effects UVB
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Zusammenfassung:	Portulaca oleracea extracts, known as Ma Chi Hyun in the traditional Korean medicine, show a variety of biomedical efficacies including those in anti‐inflammation and anti‐allergy. In this study, we investigate the protective activity of the P. oleracea extracts against UVB‐induced damage in human epithelial keratinocytes and fibroblasts by several apoptosis‐related tests. The results suggest that P. oleracea extracts have protective effects from UVB‐induced apoptosis.
ISSN:	0906-6705 1600-0625
DOI:	10.1111/exd.12396